BDBM50002088 CHEMBL302005::[11-(2-Dimethylamino-ethylidene)-6,11-dihydro-dibenzo[b,e]oxepin-2-yl]-acetic acid

SMILES CN(C)C\C=C1/c2ccccc2COc2ccc(CC(O)=O)cc12

InChI Key InChIKey=BMMSDSQQAGDCHS-RQZCQDPDSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50002088   

TargetHistamine H1 receptor(Homo sapiens (Human))
National Heart And Lung Institute

Curated by ChEMBL
LigandPNGBDBM50002088(CHEMBL302005 | [11-(2-Dimethylamino-ethylidene)-6,...)
Affinity DataKi:  11nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50002088(CHEMBL302005 | [11-(2-Dimethylamino-ethylidene)-6,...)
Affinity DataKi:  11nMAssay Description:Inhibition of the specific binding of [3H]-pyrilamine to guinea pig cerebellum histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50002088(CHEMBL302005 | [11-(2-Dimethylamino-ethylidene)-6,...)
Affinity DataKi:  11nMAssay Description:The compound was tested in vitro for binding affinity against histamine H1 receptor from guinea pig cerebellum, using [3H]pyrilamine as radioligand a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
National Heart And Lung Institute

Curated by ChEMBL
LigandPNGBDBM50002088(CHEMBL302005 | [11-(2-Dimethylamino-ethylidene)-6,...)
Affinity DataKi:  11nMAssay Description:Inhibition constant against histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
National Heart And Lung Institute

Curated by ChEMBL
LigandPNGBDBM50002088(CHEMBL302005 | [11-(2-Dimethylamino-ethylidene)-6,...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to TXA2 receptor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
National Heart And Lung Institute

Curated by ChEMBL
LigandPNGBDBM50002088(CHEMBL302005 | [11-(2-Dimethylamino-ethylidene)-6,...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition constant against thromboxane A2 receptor to prostaglandin H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed