BDBM50003490 CHEMBL101245::[4-(3,3-Diphenyl-propionyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile

SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(C#N)c1cccnc1

InChI Key InChIKey=NPVHNNBFVUFYHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003490   

TargetPlatelet-activating factor receptor(Cavia porcellus)
J. Uriach & CíA.

Curated by ChEMBL
LigandPNGBDBM50003490(CHEMBL101245 | [4-(3,3-Diphenyl-propionyl)-piperaz...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PAF-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
J. Uriach & CíA.

Curated by ChEMBL
LigandPNGBDBM50003490(CHEMBL101245 | [4-(3,3-Diphenyl-propionyl)-piperaz...)
Affinity DataIC50:  20nMAssay Description:Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed