BDBM50004340 CHEMBL3237854

SMILES Cc1nn(C)c2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN)nc12

InChI Key InChIKey=JRNRDDIKLSHPOP-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50004340   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Siedlce University Of Natural Sciences And Humanities

Curated by ChEMBL
LigandPNGBDBM50004340(CHEMBL3237854)
Affinity DataKi:  7.10nMAssay Description:Inhibition of human carbonic anhydrase 12-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Siedlce University Of Natural Sciences And Humanities

Curated by ChEMBL
LigandPNGBDBM50004340(CHEMBL3237854)
Affinity DataKi:  24nMAssay Description:Inhibition of human carbonic anhydrase 9-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Siedlce University Of Natural Sciences And Humanities

Curated by ChEMBL
LigandPNGBDBM50004340(CHEMBL3237854)
Affinity DataKi:  62nMAssay Description:Inhibition of human carbonic anhydrase 2-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Siedlce University Of Natural Sciences And Humanities

Curated by ChEMBL
LigandPNGBDBM50004340(CHEMBL3237854)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 1-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Siedlce University Of Natural Sciences And Humanities

Curated by ChEMBL
LigandPNGBDBM50004340(CHEMBL3237854)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CK2alpha1 (unknown origin) using casein as substrate in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Siedlce University Of Natural Sciences And Humanities

Curated by ChEMBL
LigandPNGBDBM50004340(CHEMBL3237854)
Affinity DataIC50:  3.49E+4nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in Sf9 cells using histone H1 as substrate in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Siedlce University Of Natural Sciences And Humanities

Curated by ChEMBL
LigandPNGBDBM50004340(CHEMBL3237854)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant Abl kinase (unknown origin) expressed in Sf9 cells using GGEAIYAAPFKK as substrate in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed