BDBM50006580 1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine; oxalic acid::CHEMBL15944::CHEMBL308608

SMILES CSc1nsnc1C1=CCCN(C)C1

InChI Key InChIKey=SGQUZSYRIZOLFQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50006580   

TargetMuscarinic acetylcholine receptor M1(RAT)
Novo Nordisk Cns Division

Curated by ChEMBL
LigandPNGBDBM50006580(1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  2.30nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Novo Nordisk Cns Division

Curated by ChEMBL
LigandPNGBDBM50006580(1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  43nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50006580(1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  1.80E+3nMAssay Description:Compound was evaluated for its ability to displace [3H]-N-methylscopolamine ([3H]-NMS) binding to cloned CHO cell lines expressing Muscarinic acetylc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50006580(1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  1.60E+3nMAssay Description:Compound was evaluated for its ability to displace [3H]-N-methylscopolamine ([3H]-NMS) binding to cloned CHO cell lines expressing Muscarinic acetylc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50006580(1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  480nMAssay Description:Compound was evaluated for its ability to displace [3H]- N-methylscopolamine ([3H]-NMS) binding to cloned CHO cell lines expressing Muscarinic acetyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50006580(1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  2.10E+3nMAssay Description:Compound was evaluated for its ability to displace [3H]- N-methylscopolamine ([3H]-NMS) binding to cloned CHO cell lines expressing Muscarinic acetyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50006580(1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  1.20E+3nMAssay Description:Compound was evaluated for its ability to displace [3H]- N-methylscopolamine ([3H]-NMS) binding to cloned CHO cell lines expressing Muscarinic acetyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed