BDBM50006812 7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydroxy-propoxy]-4-oxo-4H-chromene-2-carboxylic acid(FPL 55,712)::7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydroxy-propoxy]-4-oxo-8-propyl-4H-chromene-2-carboxylic acid::7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydroxy-propoxy]-4-oxo-8-propyl-4H-chromene-2-carboxylic acid (FPL55712)::7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydroxy-propoxy]-4-oxo-8-propyl-4H-chromene-2-carboxylic acid(FPL 55712)::7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydroxy-propoxy]-4-oxo-8-propyl-4H-chromene-2-carboxylic acid(FPL-55712)::7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydroxy-propoxy]-4-oxo-8-propyl-4H-chromene-2-carboxylic acid;FPL-55,712::CHEMBL267475
SMILES CCCc1c(OCC(O)COc2ccc3c(oc(cc3=O)C(O)=O)c2CCC)ccc(C(C)=O)c1O
InChI Key InChIKey=LMQBMWHHGVZWMR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50006812
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 940nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membraneMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor in guinea pig lung membranes using [3H]-LTD4 as the radioligand.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of SRS-A-induced contractions in guinea pig ileumMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of LTD4-induced contraction in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in ratsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Compound was tested for binding affinity against Cysteinyl leukotriene D4 receptorMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataKd: 1.12E+3nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibitory activity against cyclic GMP-phosphodiesterase (PDE V) isolated from porcine aorta.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKd: 1.12E+3nMAssay Description:Dissociation constant was determined against Cysteinyl leukotriene D4 receptor of guinea pig lung membranes using radioligand binding assays.More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(BOVINE)
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair