BDBM50006905 2-{4-[(4-Oxo-3,4-dihydro-benzo[d][1,2,3]triazin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid::CHEMBL316019

SMILES OC(=O)CCC(NC(=O)c1ccc(NCc2ccc3nn[nH]c(=O)c3c2)cc1)C(O)=O

InChI Key InChIKey=YKORUANEKZOBMT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006905   

TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006905(2-{4-[(4-Oxo-3,4-dihydro-benzo[d][1,2,3]triazin-6-...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity of the compound towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006905(2-{4-[(4-Oxo-3,4-dihydro-benzo[d][1,2,3]triazin-6-...)
Affinity DataKi:  2.80E+4nMAssay Description:Compound was tested for the inhibition of recombinant mouse thymidylate synthase, competitive with 5,10-methylenetetrahydrofolate as variable substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed