BDBM50007428 7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chromen-4-one::CHEMBL84639

SMILES O=c1ccoc2cc(OCCCN3CCN(CC3)c3ccccn3)ccc12

InChI Key InChIKey=NVGYZBZAFVGARK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50007428   

TargetD(1A) dopamine receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007428(7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chro...)
Affinity DataIC50:  2.17E+4nMAssay Description:Compound was tested for its inhibitory effect on the binding profile in Dopamine receptor D1 using [3H]flupenthixol in rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007428(7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chro...)
Affinity DataIC50:  1.08E+3nMAssay Description:Compound was tested for its inhibitory effect on the binding profile in Dopamine receptor D2 using [3H]haloperidol in rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007428(7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was tested for its inhibitory effect on the binding profile in 5-hydroxytryptamine 2 receptor using [3H]spiroperidol in rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007428(7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chro...)
Affinity DataIC50:  170nMAssay Description:Compound was tested for its inhibitory effect on the binding profile in Alpha-1 adrenergic receptor using [3H]prazosin in rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007428(7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chro...)
Affinity DataIC50:  59nMAssay Description:Compound was tested for its inhibitory effect on the binding profile in Dopamine receptor using [3H]N-propylnorapomorphine in rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50007428(7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chro...)
Affinity DataIC50:  2.60E+3nMAssay Description:Compound was tested for its inhibitory effect on the binding profile in Alpha-2 adrenergic receptor using [3H]p-aminoclonidine in rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007428(7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was tested for inhibitory binding activity against Dopamine receptor in rat striatal membranes using [3H]HAL as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed