BDBM50007457 1-[4-(8,9-Difluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone::CHEMBL342747

SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2cc(F)c(F)cc2-[#6]-[#6]-c2cccnc-12

InChI Key InChIKey=XWJJAWRVPJASIO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007457   

TargetHistamine H1 receptor(RAT)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007457(1-[4-(8,9-Difluoro-5,6-dihydro-benzo[5,6]cyclohept...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007457(1-[4-(8,9-Difluoro-5,6-dihydro-benzo[5,6]cyclohept...)
Affinity DataIC50:  1.00E+3nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed