BDBM50007550 3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro-5'H-dibenzo[a,d]cycloheptene)]-4-yl(dimethyl)amine::CHEMBL300647::Enantiomer 2'3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro-5'H-dibenzo[a,d]cycloheptene)]-4-yl(dimethyl)amine
SMILES CN(C)C1CCC2(C=C1)c1ccccc1C=Cc1ccc(Cl)cc21
InChI Key InChIKey=FZXSXMYFIZKXPT-UHFFFAOYSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50007550
Affinity DataKi: 0.300nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 0.660nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D1 using SCH-23390 as radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligandMore data for this Ligand-Target Pair