BDBM50007695 3-Piperazin-1-yl-benzo[d]isothiazole::Benzisothiazole-3-Yl-Piperazine (Bitp)::CHEMBL1154::CHEMBL1204336::EN300-230853
SMILES C1CN(CCN1)c1nsc2ccccc12
InChI Key InChIKey=KRDOFMHJLWKXIU-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50007695
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor using in rat hippocampal tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3.34E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro affinity for rat striatal Dopamine receptor D2 labeled with [3H]spiperoneMore data for this Ligand-Target Pair