BDBM50008029 (4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone::(s-cis) -(4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone::CHEMBL13178::PRAVADOLINE

SMILES COc1ccc(cc1)C(=O)c1c(C)n(CCN2CCOCC2)c2ccccc12

InChI Key InChIKey=MEUQWHZOUDZXHH-UHFFFAOYSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008029   

TargetProstaglandin-H2 D-isomerase(Mus musculus)
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50008029((4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-e...)
Affinity DataIC50:  3.50E+3nMAssay Description:Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin-H2 D-isomerase(Mus musculus)
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50008029((4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-e...)
Affinity DataIC50: >3.00E+4nMAssay Description:Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50008029((4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-e...)
Affinity DataIC50:  3.16E+3nMAssay Description:Concentration required to displace 50% of 0.5 nM [3H](aminoalkyl)indole binding to cannabinoid receptor in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed