BDBM50008523 CHEMBL4071332

SMILES CN1CCc2ccccc2C1CNC(=O)c1ccc(C)c(C)c1

InChI Key InChIKey=WVQGGZOWWCTBFN-RSSWGTIMSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50008523   

TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50008523(CHEMBL4071332)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]naloxone from recombinant human MOR expressed in HEK cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50008523(CHEMBL4071332)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human MOR expressed in CHO-K1 cells co-expressing Galpha 15 assessed as increase in intracellular calcium release incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50008523(CHEMBL4071332)
Affinity DataIC50:  80nMAssay Description:Agonist activity at human KOR expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase-mediated cAMP accumulation after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50008523(CHEMBL4071332)
Affinity DataIC50:  80nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase-mediated cAMP accumulation after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed