BDBM50009222 4-cyclopropylmethyl-14-(1H-3-indolyl)-(1S,13S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,14-tetraene-10,17-diol

SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=CC[C@@]35O)c1c[nH]c2ccccc12

InChI Key InChIKey=KNLMNSUTXWVHPN-GDOYDIOZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009222   

TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009222(4-cyclopropylmethyl-14-(1H-3-indolyl)-(1S,13S,17S)...)
Affinity DataKi:  0.630nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pigbrain membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009222(4-cyclopropylmethyl-14-(1H-3-indolyl)-(1S,13S,17S)...)
Affinity DataKi:  0.990nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor deltaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009222(4-cyclopropylmethyl-14-(1H-3-indolyl)-(1S,13S,17S)...)
Affinity DataKi:  6.20nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor kappa using [3H]-EK as radioligand in guinea pigbrain membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed