BDBM50011348 5-[2-{[2-(3-Amino-3-methyl-butyrylamino)-3-phenyl-propionyl]-methyl-amino}-3-(3H-imidazol-4-yl)-propionylamino]-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid {2-methyl-1-[(1-oxy-pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide::CHEMBL3143479

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)CC(C)(C)N)C(C)C)C(=O)NCc1cccc[n+]1[O-]

InChI Key InChIKey=CYAGIYNEKHOQEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011348   

TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011348(5-[2-{[2-(3-Amino-3-methyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed