BDBM50012149 CHEMBL3264446::US10118915, Compound 105::US9682966, 105
SMILES COC(=O)c1cc(Br)cnc1N1CC[C@@H](NC2CCCCC2)[C@H](O)C1
InChI Key InChIKey=AJYHHWYDOWTOKZ-HZPDHXFCSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50012149
Affinity DataIC50: 56nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 343nMAssay Description:Antagonist activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 323nMAssay Description:Antagonist activity at GAL4-VP16-fused MOR (unknown origin) expressed in human U2OS cells assessed as inhibition of DAMGO-induced beta-arrestin migra...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at GAL4-VP16-fused KOR (unknown origin) expressed in human U2OS cells co-expressing Tango-OPRK1-BLA assessed as inhibition of U-5...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at GAL4-VP16-fused DOR (unknown origin) expressed in human U2OS cells assessed as inhibition of DAMGO-induced beta-arrestin migra...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of SNC-80-stimulated [35S]-GTP[gammaS] bindin...More data for this Ligand-Target Pair