BDBM50012644 CHEMBL3261054

SMILES [H][C@]12CSC(N)=N[C@]1(CO[C@@H]2CF)c1cc(NC(=O)c2cnc(cn2)C(F)F)ccc1F

InChI Key InChIKey=MLVRXXWAUNGUFX-PRIMNGNOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012644   

TargetBeta-secretase 1(Rattus norvegicus)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012644(CHEMBL3261054)
Affinity DataIC50:  7nMAssay Description:Inhibition of BACE1 in Wistar rat primary neuronal cells assessed as inhibition of production of amyloid beta (1 to 42) after 3 days by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed