BDBM50013075 2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one::CHEMBL15985

SMILES O=c1[nH]c(Nc2ccc3CCCc3c2)nc2nc[nH]c12

InChI Key InChIKey=NEGTVXJJUKTMCG-UHFFFAOYSA-N

Data  1 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50013075   

TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50013075(2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one | CHEM...)
Affinity DataKi:  4.40E+4nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50013075(2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one | CHEM...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase (TK) assay for herpes simplex virus type 2 (HSV-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50013075(2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one | CHEM...)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibitory activity against HSV-1 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50013075(2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one | CHEM...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50013075(2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one | CHEM...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50013075(2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one | CHEM...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of [3H]-MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed