BDBM50015449 CHEMBL3265033

SMILES O=S1(=O)CCN(CC1)c1ccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)cc1

InChI Key InChIKey=SBFGJTSNMVBWKL-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015449   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015449(CHEMBL3265033)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015449(CHEMBL3265033)
Affinity DataIC50:  20nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed