BDBM50016136 CHEMBL3261488
SMILES NC(=O)c1sc(nc1O)-c1ccncc1
InChI Key InChIKey=LUCNVBJSQKSYBC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50016136
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Cdc7/Dbf4 in human HCT116 cells assessed as reduction of MCM2 phosphorylation after 14 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substrate by HTRF assayMore data for this Ligand-Target Pair