BDBM50016161 CHEMBL3261512

SMILES NC(=O)c1sc(nc1-c1ccccc1C(F)(F)F)-c1ccnc(N)n1

InChI Key InChIKey=TVWGRFWTJOWJTO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016161   

LigandPNGBDBM50016161(CHEMBL3261512)
Affinity DataIC50:  18nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016161(CHEMBL3261512)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of Cdc7/Dbf4 in human HCT116 cells assessed as reduction of MCM2 phosphorylation after 14 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016161(CHEMBL3261512)
Affinity DataIC50:  3.49E+4nMAssay Description:Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed