BDBM50016164 CHEMBL3261515

SMILES NC(=O)c1sc(nc1-c1cc(Cl)cc(Cl)c1)-c1ccnc(N)n1

InChI Key InChIKey=YOIXUDZDAZSIKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016164   

LigandPNGBDBM50016164(CHEMBL3261515)
Affinity DataIC50:  62nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016164(CHEMBL3261515)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of Cdc7/Dbf4 in human HCT116 cells assessed as reduction of MCM2 phosphorylation after 14 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016164(CHEMBL3261515)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed