BDBM50016165 CHEMBL3261516
SMILES Cc1ccc(-c2nc(sc2C(N)=O)-c2ccnc(N)n2)c(Cl)c1
InChI Key InChIKey=DDHMZMZQNLXNGY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50016165
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Cdc7/Dbf4 in human HCT116 cells assessed as reduction of MCM2 phosphorylation after 14 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.03E+3nMAssay Description:Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substrate by HTRF assayMore data for this Ligand-Target Pair