BDBM50018556 (+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione::(+/-)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione::(-)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione::1'-Benzyl-3-phenyl-[3,4']bipiperidinyl-2,6-dione::CHEMBL10272::Dexetimide1'-Benzyl-3-phenyl-[3,4']bipiperidinyl-2,6-dione

SMILES O=C1CCC(C2CCN(Cc3ccccc3)CC2)(C(=O)N1)c1ccccc1

InChI Key InChIKey=LQQIVYSCPWCSSD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50018556   

TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018556((+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018556((+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Mus musculus)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018556((+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione...)
Affinity DataIC50:  8.90E+3nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018556((+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018556((+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018556((+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed