BDBM50019174 (R)-4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide::(S)-4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide::4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide::CHEMBL40211

SMILES CN1c2ccccc2C(=NC(NC(=O)c2ccc(Cl)cc2)C1=O)c1ccccc1F

InChI Key InChIKey=IRUDQSQIPJJXFZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50019174   

TargetCholecystokinin receptor type A(RAT)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50019174((R)-4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo...)
Affinity DataIC50:  2.29nMAssay Description:Binding affinity against cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50019174((R)-4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo...)
Affinity DataIC50:  2.30nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019174((R)-4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo...)
Affinity DataIC50:  3.40E+3nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50019174((R)-4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo...)
Affinity DataIC50:  2.29nMAssay Description:Binding affinity against cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019174((R)-4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo...)
Affinity DataIC50:  2.90E+3nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed