BDBM50019250 5-(2-Fluoro-phenyl)-1-methyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one::CHEMBL13095::Ro-05-4520
SMILES CN1c2ccccc2C(=NCC1=O)c1ccccc1F
InChI Key InChIKey=YVTVBCWQHDDTGB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50019250
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 7.14E+7nMAssay Description:Binding affinity of compound towards Benzodiazepine receptor in a competition assayMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.20E+4nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair