BDBM50019671 2-Isopropoxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid (4-pyridin-3-yl-butyl)-amide::CHEMBL57716

SMILES CC(C)Oc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cccnc1

InChI Key InChIKey=OCWOTYUFXGGBAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019671   

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50019671(2-Isopropoxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019671(2-Isopropoxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8...)
Affinity DataIC50:  600nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed