BDBM50019683 11-Oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid (4-pyridin-3-yl-butyl)-amide::CHEMBL60625

SMILES O=C(NCCCCc1cccnc1)c1ccc2nc3ccccc3c(=O)n2c1

InChI Key InChIKey=LTXALSZKGGRIKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019683   

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50019683(11-Oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic a...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019683(11-Oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic a...)
Affinity DataIC50:  1.80E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed