BDBM50019690 2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid (2-pyridin-3-yl-ethyl)-amide::CHEMBL1204218::CHEMBL418141

SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCc1cccnc1

InChI Key InChIKey=FQHVTWFSIXJLNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019690   

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50019690(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019690(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed