BDBM50022180 5,7-Dihydroxy-4-methyl-2H-chromen-2-one (2)::5,7-Dihydroxy-4-methyl-chromen-2-one::5,7-dihydroxy-4-methyl-2H-chromen-2-one::CHEMBL12252::Coumarin derivative, 1b
SMILES Cc1cc(=O)oc2cc(O)cc(O)c12
InChI Key InChIKey=QNVWGEJMXOQQPM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50022180
Affinity DataKi: 190nM ΔG°: -8.52kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nM ΔG°: -6.58kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 8.40E+3nM ΔG°: -6.43kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+5nM ΔG°: >-4.69kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Umdnj-New Jersey Medical School
Umdnj-New Jersey Medical School
Affinity DataIC50: 4.72E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using HCV NS5B.More data for this Ligand-Target Pair