BDBM50023642 CHEMBL3144193::Phosphoric acid mono-{5-[5-(4-cyano-phenyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-3-hydroxy-tetrahydro-furan-2-ylmethyl} ester

SMILES O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)n1cc(-c2ccc(cc2)C#N)c(=O)[nH]c1=O

InChI Key InChIKey=HDOUTIGHYBDMMB-UHFFFAOYSA-L

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50023642   

TargetThymidylate synthase(Lactobacillus casei)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50023642(CHEMBL3144193 | Phosphoric acid mono-{5-[5-(4-cyan...)
Affinity DataKi:  8.75E+3nMAssay Description:Inhibitory effect on Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50023642(CHEMBL3144193 | Phosphoric acid mono-{5-[5-(4-cyan...)
Affinity DataKi:  9.78E+4nMAssay Description:Inhibitory effect on murine leukemia (L1210) thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50023642(CHEMBL3144193 | Phosphoric acid mono-{5-[5-(4-cyan...)
Affinity DataKi:  1.14E+5nMAssay Description:Inhibitory effect on human lymphoblast (Molt/4F) thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed