BDBM50025026 CHEMBL3337847

SMILES COc1cncc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1

InChI Key InChIKey=HXESGMYSKDHCFX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025026   

TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025026(CHEMBL3337847)
Affinity DataIC50:  990nMAssay Description:Inhibition of human recombinant CK1epsilon expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025026(CHEMBL3337847)
Affinity DataIC50:  270nMAssay Description:Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025026(CHEMBL3337847)
Affinity DataIC50:  560nMAssay Description:Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed