BDBM50026277 2-(4-{[(2,4-Diamino-quinazolin-6-yl)-formyl-amino]-methyl}-benzoylamino)-pentanedioic acid::CHEMBL69713

SMILES Nc1nc(N)c2cc(ccc2n1)N(Cc1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O)C=O

InChI Key InChIKey=RUGCGRLQNAZXOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026277   

TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026277(2-(4-{[(2,4-Diamino-quinazolin-6-yl)-formyl-amino]...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of rat liver dihydrofolate reductase assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed