BDBM50026622 CHEMBL408982
SMILES CCN1\C(Sc2ccc(OC)cc12)=C\C(C)=O
InChI Key InChIKey=BGVLELSCIHASRV-QPEQYQDCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50026622
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human C-terminus CLK1 (148 to 484 residues) expressed in Escherichia coli BL21(DE3) using AFRREWSPGKEAKK as substrate preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged mouse CLK4 expressed in Escherichia coli using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH as substrate after 10 mins in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk1 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk2 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk4 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Mus musculus)
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Dyrk1A expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide...More data for this Ligand-Target Pair