BDBM50026622 CHEMBL408982

SMILES CCN1\C(Sc2ccc(OC)cc12)=C\C(C)=O

InChI Key InChIKey=BGVLELSCIHASRV-QPEQYQDCSA-N

Data  14 IC50  6 Kd

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50026622   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50:  49nMAssay Description:Inhibition of human C-terminus CLK1 (148 to 484 residues) expressed in Escherichia coli BL21(DE3) using AFRREWSPGKEAKK as substrate preincubated for ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Mus musculus)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50:  15nMAssay Description:Inhibition of GST-tagged mouse CLK4 expressed in Escherichia coli using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH as substrate after 10 mins in presence o...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Mus musculus)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50:  20nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk1 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Mus musculus)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50:  200nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk2 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Mus musculus)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50:  15nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk4 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Mus musculus)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Dyrk1A expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide...More data for this Ligand-Target Pair
In DepthDetails PubMed