BDBM50029391 2-{4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL92896

SMILES OCCN1CCN(CC1)C1CC(c2c1cccc2Cl)c1ccc(F)cc1

InChI Key InChIKey=ADWYWJGQPNBBNY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029391   

TargetD(1A) dopamine receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029391(2-{4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50:  2.00E+3nMAssay Description:The compound was tested for the binding affinity against Dopamine receptor D1 activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029391(2-{4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50:  220nMAssay Description:Binding affinity against dopamine receptor D2 More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029391(2-{4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50:  40nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029391(2-{4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50:  30nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029391(2-{4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50:  220nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed