BDBM50029632 3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxylic acid amide::CHEMBL6248

SMILES COc1ccc2sc(C(N)=O)c(OC(C)C)c2c1

InChI Key InChIKey=YNXSDBVUOOEWIK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029632   

TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50029632(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Affinity DataIC50:  390nMAssay Description:Tested for inhibition of ICAM expression by ELISA at the dose of 30 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50029632(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Affinity DataIC50:  700nMAssay Description:Tested for inhibition of E-selectin expression by ELISA at the dose of 30 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50029632(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Affinity DataIC50:  50nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029632(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Affinity DataIC50:  175nMAssay Description:In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50029632(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Affinity DataIC50:  140nMAssay Description:In vitro potency against TNF alpha induced expresion of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed