BDBM50029838 3-[5-(4-Benzyloxy-phenyl)-2-thioxo-[1,3,4]oxadiazol-3-yl]-propionitrile::CHEMBL17079
SMILES S=c1oc(nn1CCC#N)-c1ccc(OCc2ccccc2)cc1
InChI Key InChIKey=RXAQDNHMCJIVSL-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50029838
Affinity DataIC50: 47nMAssay Description:Compound was evaluated for the time-dependence inhibition of MAO-B at 0 minute pre-incubation periodsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Compound was evaluated for the time-dependence inhibition of MAO-B at 60 minutes preincubation periodsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was evaluated for the time-dependence inhibition of MAO-A at 60 minutes of preincubated period. values are same with or without pre-incubati...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:In vitro inhibitory activity on rat brain MAO-B.More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Compound was evaluated for the time-dependence inhibition of MAO-B at 30 minutes pre-incubation periodsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 120 mins by radiochemical methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
FacultéS Universitaires Notre-Dame De La Paix
Curated by ChEMBL
FacultéS Universitaires Notre-Dame De La Paix
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibitory concentration against Monoamine oxidase B was measured in baboon liver.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibitory activity on rat brain by monoamine oxidase A (MAO-A)More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Compound was evaluated for the time-dependence inhibition of MAO-B at 20 minutes pre-incubation periodsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 60 mins by radiochemical methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Compound was evaluated for the Inhibition of Monoamine oxidase BMore data for this Ligand-Target Pair