BDBM50030116 (S)-3-(1H-Indol-3-yl)-2-(3-methyl-ureido)-propionic acid 3,5-dimethyl-benzyl ester::CHEMBL23851

SMILES CNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(C)cc(C)c1

InChI Key InChIKey=MPQNAZQWGVSYGU-FQEVSTJZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50030116   

TargetNeuromedin-K receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030116((S)-3-(1H-Indol-3-yl)-2-(3-methyl-ureido)-propioni...)
Affinity DataIC50: >5.00E+3nMAssay Description:Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030116((S)-3-(1H-Indol-3-yl)-2-(3-methyl-ureido)-propioni...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030116((S)-3-(1H-Indol-3-yl)-2-(3-methyl-ureido)-propioni...)
Affinity DataIC50:  103nMAssay Description:Inhibition of cloned human NK1 (Neurokinin 1) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030116((S)-3-(1H-Indol-3-yl)-2-(3-methyl-ureido)-propioni...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of cloned human NK2 (Neurokinin 2) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030116((S)-3-(1H-Indol-3-yl)-2-(3-methyl-ureido)-propioni...)
Affinity DataIC50:  103nMAssay Description:Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed