BDBM50031650 2-[3-(4-Benzyloxy-phenyl)-2-dimethylaminomethyl-3-oxo-propylsulfanyl]-benzoic acid methyl ester; hydrochloride::CHEMBL538757

SMILES COC(=O)c1ccccc1SCC(CN(C)C)C(=O)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=ZCKJJEAXMUMRLO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031650   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Ciba

Curated by ChEMBL
LigandPNGBDBM50031650(2-[3-(4-Benzyloxy-phenyl)-2-dimethylaminomethyl-3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of the v-abl tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba

Curated by ChEMBL
LigandPNGBDBM50031650(2-[3-(4-Benzyloxy-phenyl)-2-dimethylaminomethyl-3-...)
Affinity DataIC50:  8.80E+3nMAssay Description:In vitro inhibition of the Epidermal growth factor receptor activity in A431 membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba

Curated by ChEMBL
LigandPNGBDBM50031650(2-[3-(4-Benzyloxy-phenyl)-2-dimethylaminomethyl-3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of the c-src tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed