BDBM50034932 6-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL281803
SMILES COc1ccc(OC)c(c1)N(C)Cc1cnc2nc(N)nc(N)c2c1C
InChI Key InChIKey=ZADZOIWPCBRVKE-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50034932
Affinity DataIC50: 216nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 407nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 407nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 407nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from rat liver (rl)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 30.1nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Toxoplasma gondii(tg)More data for this Ligand-Target Pair
Affinity DataIC50: 216nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii(pc)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 30.1nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 216nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair