BDBM50034961 6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4-diamine::CHEMBL53912
SMILES Nc1nc(Cl)cc(Nc2ccc(Cl)c(Cl)c2)n1
InChI Key InChIKey=IPNLIYUZWFQPKO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50034961
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Stanford University Medical School
Curated by ChEMBL
Stanford University Medical School
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition against DNA polymerase by direct assay with activated DNA and 25 uM dNTPs lacking the expected competitor substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition against DNA topoisomerase I by direct assay with activated DNA and 25 uM dNTPs including [3H]-dTTPMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Stanford University Medical School
Curated by ChEMBL
Stanford University Medical School
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition against DNA polymerase by direct assay with activated DNA and 25 uM dNTPs lacking the expected competitor substrateMore data for this Ligand-Target Pair
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School
Curated by ChEMBL
Stanford University Medical School
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair