BDBM50034988 11-Amino-undecanoic acid {(S)-1-[(S)-5-amino-1-(2-cyclohexyl-ethylcarbamoyl)-pentylcarbamoyl]-2-hydroxy-ethyl}-amide::CHEMBL33289

SMILES NCCCCCCCCCCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1

InChI Key InChIKey=ZHXMOHGSCCLPTR-DQEYMECFSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50034988   

TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50034988(11-Amino-undecanoic acid {(S)-1-[(S)-5-amino-1-(2-...)
Affinity DataKi:  70nMAssay Description:Apparent binding affinity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50034988(11-Amino-undecanoic acid {(S)-1-[(S)-5-amino-1-(2-...)
Affinity DataKi:  90nMAssay Description:Apparent binding affinity against Human NMT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50034988(11-Amino-undecanoic acid {(S)-1-[(S)-5-amino-1-(2-...)
Affinity DataIC50:  500nMAssay Description:Tested for Inhibitory concentration against human N-myristoyltransferase (NMT) in radiochemical HPLC end point assay with peptide GNAASARR-NH2 and [3...More data for this Ligand-Target Pair
In DepthDetails
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50034988(11-Amino-undecanoic acid {(S)-1-[(S)-5-amino-1-(2-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Candida albicans N-myristoyltransferase (NMT) with peptide GNAASARR-NH2 and [3H]myristoyl-CoA at 1 uMMore data for this Ligand-Target Pair
In DepthDetails
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50034988(11-Amino-undecanoic acid {(S)-1-[(S)-5-amino-1-(2-...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against human N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50034988(11-Amino-undecanoic acid {(S)-1-[(S)-5-amino-1-(2-...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Candida albicans (Yeast))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50034988(11-Amino-undecanoic acid {(S)-1-[(S)-5-amino-1-(2-...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against N-myristoyltransferase (NMT) of candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed