BDBM50036126 2-(5-Amino-6-oxo-2-thiophen-2-yl-6H-pyrimidin-1-yl)-N-(3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-acetamide::CHEMBL11084

SMILES CC(C)C(NC(=O)Cn1c(ncc(N)c1=O)-c1cccs1)C(=O)C(F)(F)F

InChI Key InChIKey=NEIDWSCQVXGHGF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036126   

TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036126(2-(5-Amino-6-oxo-2-thiophen-2-yl-6H-pyrimidin-1-yl...)
Affinity DataKi:  52nMAssay Description:In vitro inhibition of human leukocyte elastase mediated hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-pNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed