BDBM50036421 (S)-2-Amino-3-{3,5-dibromo-4-[4-hydroxy-3-(6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxy]-phenyl}-propionic acid::2-Ammonio-3-{3,5-dibromo-4-[4-hydroxy-3-(6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxy]-phenyl}-propionic acid anion::CHEMBL163228

SMILES N[C@@H](Cc1cc(Br)c(Oc2ccc(O)c(Cc3ccc(=O)[nH]n3)c2)c(Br)c1)C(O)=O

InChI Key InChIKey=BPCRJQJRJFLQHV-INIZCTEOSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036421   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50036421((S)-2-Amino-3-{3,5-dibromo-4-[4-hydroxy-3-(6-oxo-1...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [125I]-T3 from human TRalpha expressed in insect cells after 16 to 48 hrs by gamma-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50036421((S)-2-Amino-3-{3,5-dibromo-4-[4-hydroxy-3-(6-oxo-1...)
Affinity DataKi:  238nMAssay Description:Displacement of [125I]-T3 from human TRbeta expressed in insect cells after 16 to 48 hrs by gamma-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036421((S)-2-Amino-3-{3,5-dibromo-4-[4-hydroxy-3-(6-oxo-1...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036421((S)-2-Amino-3-{3,5-dibromo-4-[4-hydroxy-3-(6-oxo-1...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of bound [125I]L-T3 rat plasma membrane 3,5,3'' L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed