BDBM50037286 (1S,3S,4S,5R,6R,7R)-1-((4R,5S)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4,7-dihydroxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid::CHEMBL86319

SMILES CC[C@H](C)C[C@H](C)\C=C\C(=O)O[C@@H]1[C@@H](O)[C@]2(CCC(=C)[C@H](OC(C)=O)[C@@H](C)Cc3ccccc3)O[C@@]1(C(O)=O)[C@@](O)([C@H](O2)C(O)=O)C(O)=O

InChI Key InChIKey=DFKDOZMCHOGOBR-QQBIHXAQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037286   

TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50037286((1S,3S,4S,5R,6R,7R)-1-((4R,5S)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50037286((1S,3S,4S,5R,6R,7R)-1-((4R,5S)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Squalene synthase activity in juvenile male rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Homo sapiens (Human))
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50037286((1S,3S,4S,5R,6R,7R)-1-((4R,5S)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  5nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed