BDBM50037448 6-Dimethylamino-2-(3-methoxy-phenyl)-1H-quinolin-4-one::CHEMBL301589

SMILES COc1cccc(c1)-c1cc(O)c2cc(ccc2n1)N(C)C

InChI Key InChIKey=QWTLGBXHTGTPMU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037448   

TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50037448(6-Dimethylamino-2-(3-methoxy-phenyl)-1H-quinolin-4...)
Affinity DataIC50:  380nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037448(6-Dimethylamino-2-(3-methoxy-phenyl)-1H-quinolin-4...)
Affinity DataIC50:  380nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed