BDBM50037811 CHEMBL123016::{(S)-1-[(S)-3-Benzylcarbamoyl-1-(4-benzyloxy-benzyl)-3,3-difluoro-2-oxo-propylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)C(F)(F)C(=O)NCc1ccccc1

InChI Key InChIKey=WJSVMBNINJAEAH-LQJZCPKCSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037811   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50037811(CHEMBL123016 | {(S)-1-[(S)-3-Benzylcarbamoyl-1-(4-...)
Affinity DataKi:  5nMAssay Description:Compound was evaluated in vitro for the ability to inhibit HIV-protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50037811(CHEMBL123016 | {(S)-1-[(S)-3-Benzylcarbamoyl-1-(4-...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity of the compound was determined against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50037811(CHEMBL123016 | {(S)-1-[(S)-3-Benzylcarbamoyl-1-(4-...)
Affinity DataKi:  5nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article