BDBM50038047 2-(9-Bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyrido[1,2,3-de]quinoxalin-5-yl)-N-phenyl-acetamide::CHEMBL290738

SMILES Brc1cc2CCC(CC(=O)Nc3ccccc3)n3c2c(c1)[nH]c(=O)c3=O

InChI Key InChIKey=KPMYRXGASZVFJC-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50038047   

TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50038047(2-(9-Bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyri...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]DCKA from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50038047(2-(9-Bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyri...)
Affinity DataKi:  2.60nMAssay Description:Affinity for the glycine binding site of the NMDA receptor using [3H]- 5,7- dichloro -kynurenic acid as radio-ligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50038047(2-(9-Bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyri...)
Affinity DataIC50: >2.50E+4nMAssay Description:Displacement of [3H]kainic acid from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50038047(2-(9-Bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyri...)
Affinity DataIC50:  4.60E+3nMAssay Description:Displacement of [3H]AMPA from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50038047(2-(9-Bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyri...)
Affinity DataIC50: >2.50E+4nMAssay Description:Displacement of [3H]CGP-39653 from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed