BDBM50038846 6-fluoro-2-(5-trifluoromethylbenzo[d][1,3]thiazol-2-ylmethyl)spiro[1,2,3,4-tetrahydroisoquinoline-4,3'-(tetrahydro-1'H-pyrrole)]-1,2',3,5'-tetraone::6-fluoro-2-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone::CHEMBL10552
SMILES Fc1ccc2C(=O)N(Cc3nc4cc(ccc4s3)C(F)(F)F)C(=O)C3(CC(=O)NC3=O)c2c1
InChI Key InChIKey=GSAJQGVLZBMWHB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50038846
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair