BDBM50038846 6-fluoro-2-(5-trifluoromethylbenzo[d][1,3]thiazol-2-ylmethyl)spiro[1,2,3,4-tetrahydroisoquinoline-4,3'-(tetrahydro-1'H-pyrrole)]-1,2',3,5'-tetraone::6-fluoro-2-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone::CHEMBL10552

SMILES Fc1ccc2C(=O)N(Cc3nc4cc(ccc4s3)C(F)(F)F)C(=O)C3(CC(=O)NC3=O)c2c1

InChI Key InChIKey=GSAJQGVLZBMWHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038846   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50038846(6-fluoro-2-(5-trifluoromethylbenzo[d][1,3]thiazol-...)
Affinity DataIC50:  144nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50038846(6-fluoro-2-(5-trifluoromethylbenzo[d][1,3]thiazol-...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed