BDBM50038858 2-(1,3-benzothiazol-2-ylmethyl)-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidin::CHEMBL292486

SMILES O=C1CC2(C(=O)N1)C(=O)N(Cc1nc3ccccc3s1)C(=O)c1ccccc21

InChI Key InChIKey=XDZFFOPLWNJUMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038858   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50038858(2-(1,3-benzothiazol-2-ylmethyl)-1H,2'H,5'H-spiro[i...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed