BDBM50039183 CHEMBL72850::{(S)-2-Benzyl-3-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-yl]-propionylamino}-acetic acid

SMILES CC1CN(C[C@H](Cc2ccccc2)C(=O)NCC(O)=O)CCC1(C)c1cccc(O)c1

InChI Key InChIKey=UPNUIXSCZBYVBB-PSWPWZSKSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039183   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50039183(CHEMBL72850 | {(S)-2-Benzyl-3-[4-(3-hydroxy-phenyl...)
Affinity DataKi:  0.770nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]-NAL radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50039183(CHEMBL72850 | {(S)-2-Benzyl-3-[4-(3-hydroxy-phenyl...)
Affinity DataKi:  4.40nMAssay Description:Tested for binding affinity towards delta receptor in rat brain homogenates using [3H]-D-Ala2-D-Leu3-enkephalin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50039183(CHEMBL72850 | {(S)-2-Benzyl-3-[4-(3-hydroxy-phenyl...)
Affinity DataKi:  40nMAssay Description:Tested for binding affinity towards kappa receptor in presence of [3H]-EKC radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed